In this lesson, students will learn about ions, ion channels, and the role of chloride ions in the lungs, explore ion-dipole interactions and how chloride helps cilia function, and study the cystic fibrosis transmembrane conductance regulator (CFTR) mutation that causes cystic fibrosis by drawing models of healthy vs. cystic fibrosis transmembrane conductance regulator lung cells.

Grade Levels: 9-12

Standard:
NGSS: PS1-1
PS1-3

Topics: Biology, Biochemistry, Chemistry, Physiology

Contributor: Kirstin Blase, Villa Duchesne Upper School

Acknowledgements: The contents of this curriculum were co-developed with Dr. Michael Vahey at McKelvey School of Engineering at WashU and were funded by a grant from the National Science Foundation (CAREER: Assembly and Function of Viral Immune Complexes, MCB-2238165). These contents do not necessarily represent the policies of the National Science Foundation, and you should not assume endorsement by the federal government.